| Factor Information | |
|---|---|
| Data ID | 2170 |
| Factor | association between postoperative DTI measures of average diffusivity and preoperative brain injury score (coefficients) |
| Description | In the preoperative longitudinal analyses, we examined whether preoperative BIS predicted postoperative DTI and MRSI values. An increasing preoperative brain injury score was associated with higher postoperative Dav (p = 0.002) (figure) and higher lactate/choline (p = 0.008) |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To determine the relationship between radiologically identifiable brain injuries and delayed brain development as reflected by brain metabolic and microstructural integrity. |
| p Value | 0.002 |
| Conclusion | In the preoperative longitudinal analyses, we examined whether preoperative BIS predicted postoperative DTI and MRSI values. An increasing preoperative brain injury score was associated with higher postoperative Dav (p = 0.002) (figure) and higher lactate/choline (p = 0.008) |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 587 |
| CHD Type | isolated CHD |
| CHD Subtype | TGA/SV/AC/PA/TOF/TA/TAPVC |
| Reference | |
|---|---|
| PMID | 23771484 |
| Year | 2013 |
| Title | Brain injury and development in newborns with critical congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | a dual-center prospective cohort study | |
| Region | Vancouver, Canada | |
| Method | Longitudinal analyses | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Preoperative brain injury score(Treatment) | N/A(Control) |
| Number | 120 | N/A |
| Age | 5 days (range 1–43) | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 0.013(coefficients) | N/A |
