| Factor Information | |
|---|---|
| Data ID | 2174 |
| Factor | Clinical predictors of brain injury severity：preoperative variables: preoperative hypotension |
| Description | Higher neonatal illness severity scores (p = 0.03), lower preoperative oxygen saturation (p = 0.002), hypotension (p < 0.001), and septostomy (p = 0.002) were also predictive of higher preoperative BIS. |
| Biomarker | YES |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To determine the relationship between radiologically identifiable brain injuries and delayed brain development as reflected by brain metabolic and microstructural integrity. |
| p Value | <0.001 |
| Conclusion | Higher neonatal illness severity scores (p = 0.03), lower preoperative oxygen saturation (p = 0.002), hypotension (p < 0.001), and septostomy (p = 0.002) were also predictive of higher preoperative BIS. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 587 |
| CHD Type | isolated CHD |
| CHD Subtype | TGA/SV/AC/PA/TOF/TA/TAPVC |
| Reference | |
|---|---|
| PMID | 23771484 |
| Year | 2013 |
| Title | Brain injury and development in newborns with critical congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | a dual-center prospective cohort study | |
| Region | Vancouver, Canada | |
| Method | collect clinical data | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | UBC= British Columbia Children’s Hospital, University of British Columbia(Treatment) | UCSF= University of California San Francisco Benioff Children’s Hospital(Control) |
| Number | 36 | 84 |
| Age | 5 days (range 1–43) | 5 days (range 1–43) |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 7 (20%) | 38 (48%) |
