| Factor Information | |
|---|---|
| Data ID | 2242 |
| Factor | Interval between renovation and moving-in(<1 months)--3 months before pregnancy |
| Description | An increased risk for giving birth to offspring with cardiac defects was found in only two groups where the mother moved into the decorated house either during 3 months before pregnancy (AOR: 2.38, 95%CI:1.03 to 5.48) or the first trimester (AOR: 4.00, 95%CI: 1.62 to 9.86), when the move-in occurred less than one month after renovation. |
| Biomarker | NA |
| Classification | B3 (environmental factor - exposure history) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | The study focused on the potential effect of maternal exposure to housing renovations on the risk of CHD in offspring, as well as, assessed the critical exposure window. |
| p Value | 0.042 |
| OR | 2.38 |
| Conclusion | An increased risk for giving birth to offspring with cardiac defects was found in only two groups where the mother moved into the decorated house either during 3 months before pregnancy (AOR: 2.38, 95%CI:1.03 to 5.48) or the first trimester (AOR: 4.00, 95%CI: 1.62 to 9.86), when the move-in occurred less than one month after renovation. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 592 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | VSD/ASD/TGA/CoA/IAA/other |
| Reference | |
|---|---|
| PMID | 23522351 |
| Year | 2013 |
| Title | Association between maternal exposure to housing renovation and offspring with congenital heart disease: a multi-hospital case-control study. |
| Sample | ||
|---|---|---|
| Population | pregnant women | |
| Source | questionnaire | |
| Region | Sichuan, China | |
| Method | A multi-hospital case-control study was designed to investigate the association between maternal periconceptional housing renovation exposure and the risk of CHD for offspring. | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Isolated cardiac defects(Treatment) | Controls(Control) |
| Number | 18 | 13 |
| Age | <20, 20-35, >35 years | <20, 20-35, >35 years |
| Gender (Male: Female) | 0:281 | 0:408 |
| Marker Level | 18 (6.4%) | 13 (3.2%) |
