| Factor Information | |
|---|---|
| Data ID | 2307 |
| Factor | Cardiothoracic ratio--In Relation to Lung Function |
| Description | Moderate to severe impairment of lung function related to complexity of underlying cardiac defect, enlarged cardiothoracic ratio, previous thoracotomy/ies, body mass index, scoliosis, and diaphragm palsy. |
| Biomarker | YES |
| Classification | A6 (clinical factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | We investigated the prevalence of abnormal lung function, its relation to severity of underlying cardiac defect, its surgical history, and its impact on outcome across the spectrum of adult congenital heart disease. |
| p Value | <0.001 |
| Conclusion | Mildly impairment of lung function related to enlarged cardiothoracic ratio, lung hypoperfusion, amiodarone, surgical history. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 595 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/VSD/AC/TGA/AVSD/ccTGA/EA/TOF/other |
| Reference | |
|---|---|
| PMID | 23382015 |
| Year | 2013 |
| Title | Abnormal lung function in adults with congenital heart disease: prevalence, relation to cardiac anatomy, and association with survival. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | a retrospective study | |
| Region | London,UK | |
| Method | collect and classify | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | Surgical repair/palliation | |
| Group | mildly Impaired of lung function(Treatment) | Normal(Control) |
| Number | 207(total) | 628(total) |
| Age | 32.7±14.1 years | 33.7±12.8 years |
| Gender (Male: Female) | 115:92 | 349:279 |
| Marker Level | 54.7±7.0 % | 51.5±6.8 % |
