Factor Information
Data ID 2336
Factor HCT (Hematocrit) (%)
Description In the cyanotic CHD group, hemoglobin and hematocrit concentrations were statistically significantly higher while platelet count was lower.
Biomarker NA
Classification E11 (physiological factor - physical sign)
Association
Application prognosis
Objective To assess endothelial dysfunction and the risk for coronary atherosclerosis in children with irreversible pulmonary hypertension due to CHD.
p Value <0.001
Conclusion Systemic endothelial dysfunction in children with irreversible pulmonary hypertension due to CHD was noted but there was no increased risk for atherosclerosis.
Risk Factor unknown
CHD Type
ID 148
CHD Type NA
CHD Subtype NA
Reference
PMID 23129906
Year 2012
Title Endothelial dysfunction and atherosclerosis in children with irreversible pulmonary hypertension due to congenital heart disease.
Sample
Population Children
Source Blood, Lipid
Region Antalya, Turkey
Method flow-mediated dilatation (FMD), carotid intima media thickness (CIMT), atherosclerotic risk factors, Detection of endothelial dysfunction, Measurement of carotid artery intima media thickness
Race Asia
Disease History cyanotic patients
Treatment History N/A
Group cyanotic patients (patients with irreversible PAH due to CHD)(Treatment) control patients (children with no hypertension, diabetes mellitus and obesity)(Control)
Number 18 18
Age 12.28 ± 3.26 years 11.78 ± 3.00 years
Gender (Male: Female) 8:10 8:10
Marker Level 50.45 ± 7.76 % 38.85 ± 3.22 %