| Factor Information | |
|---|---|
| Data ID | 2345 |
| Factor | Spirometry suggestive of restrictive lung disease |
| Description | Spirometry suggestive of RLD was a significant risk factor for decreased exercise capacity (odds ratio = 3.65, P = .03). Along with traditional predictors such as decreased chronotropic index and heart rate reserve, we found that spirometry suggestive of RLD was a strong predictor of exercise intolerance by multivariate analysis with an odds ratio of 3.65 (P = 0.03). |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | decreased exercise capacity |
| p Value | <0.05 |
| OR | >3.0 |
| Conclusion | Abnormal spirometry suggestive of RLD is common in the adult with CHD and is a significant risk factor for decreased exercise tolerance in this population. Spirometry suggestive of RLD was a significant risk factor for decreased exercise capacity (odds ratio = 3.65, P=0.03). |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 599 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | CoA/TOF/LVOTO/ASD, VSD, AVSD/SV/D-TGA/ccTGA/EA/PVS |
| Reference | |
|---|---|
| PMID | 23075089 |
| Year | 2012 |
| Title | Restrictive lung disease is an independent predictor of exercise intolerance in the adult with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | N/A | |
| Region | Milwaukee, USA | |
| Method | routine cardiopulmonary exercise testing with spirometry | |
| Race | North American | |
| Disease History | N/A | |
| Treatment History | Most patients, 79%, had at least one previous surgical procedure. | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | N/A | N/A |
| Age | 31 (18–63) years | 31 (18–63) years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | N/A | N/A |
