| Factor Information | |
|---|---|
| Data ID | 2350 |
| Factor | percentage of Restrictive lung disease(RLD) in TOF |
| Description | Patients with TOF were also more likely to have spirometry suggestive of RLD (13/17, 76%, P = .05). Patients with a history of Fontan palliation for single ventricle physiology and TOF were significantly more likely to have abnormal spirometry suggestive of RLD. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | RLD (Restrictive lung disease) |
| p Value | 0.05 |
| Conclusion | Abnormal spirometry suggestive of RLD is common in the adult with CHD and is a significant risk factor for decreased exercise tolerance in this population. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 53 |
| CHD Type | isolated CHD |
| CHD Subtype | TOF |
| Reference | |
|---|---|
| PMID | 23075089 |
| Year | 2012 |
| Title | Restrictive lung disease is an independent predictor of exercise intolerance in the adult with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | N/A | |
| Region | Milwaukee, USA | |
| Method | routine cardiopulmonary exercise testing with spirometry | |
| Race | North American | |
| Disease History | N/A | |
| Treatment History | Most patients, 79%, had at least one previous surgical procedure. | |
| Group | Abnormal spirometry suggestive of RLD(Treatment) | Normal spirometry suggestive of RLD(Control) |
| Number | 13 (total: 17) | 4 (total: 17) |
| Age | 34 (18–55) years | 34 (18–55) years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | RLD: 13(76%) | RLD: 4 (24%) |
