| Factor Information | |
|---|---|
| Data ID | 2382 |
| Factor | NT-proBNP [pg/mL] |
| Description | Mean NTproBNP serum-levels slightly decreased after 3 weeks of exercise training and significantly increased after 15 weeks (p=0.031) |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | to assess the efficacy of exercise training as add-on to medical therapy in patients with congenital heart disease associated pulmonary arterial hypertension. |
| p Value | 0.031 |
| Conclusion | Exercise training as add-on to medical therapy may be effective in patients with CHD–APAH and improved work capacity, quality of life and further prognostic relevant parameters. It was associated with an excellent long-term survival. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 101 |
| CHD Type | isolated CHD |
| CHD Subtype | CHD with PAH |
| Reference | |
|---|---|
| PMID | 23041100 |
| Year | 2013 |
| Title | Efficacy of exercise training in pulmonary arterial hypertension associated with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | N/A | |
| Source | N/A | |
| Region | Heidelberg, Germany | |
| Method | invasively | |
| Race | European | |
| Disease History | N/A | |
| Treatment History | Medical treatment; a new PAH-targeted medical treatment and the start of exercise training | |
| Group | 15 weeks of exercise training(Treatment) | baseline(Control) |
| Number | 15 | 20 |
| Age | 48±11 (41–55) years | 48±11 (41–55) years |
| Gender (Male: Female) | N/A | 4:16 |
| Marker Level | 651±565 pg/mL | 493±471 pg/mL |
