| Factor Information | |
|---|---|
| Data ID | 2476 |
| Factor | risk factors for all the events (early and late death): preoperative mechanical ventilation |
| Description | The univariate risk factors for all the events (early and late death) included urgency status (hazard ratio [HR] 2.7; 95% confidence interval [CI] 1.21–6.15) and preoperative mechanical ventilation (HR 4.47; 95% CI 1.97–10.9). Multivariate analysis for all events (early and late deaths) identified preoperative mechanical ventilation as an indepedent risk factor for mortality (HR 4.47; 95% CI 1.97–10.1). |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | early and late deaths |
| HR | 4.47 |
| Conclusion | We demonstrated that heart transplantation for patients with CHD can be performed with the expectation of excellent results. Previous procedures, including the Fontan operation, do not reduce survival. Mortality is related to preoperative patient condition. We advocate early referral of complex CHD patients for transplant assessment and for inclusion in waiting lists before the detrimental effects of end-stage failure manifest themselves. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 603 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | UVH/TA/DILV, PA/DILV, PS/DILV/UVH, TGA/HLHS/DOLV/UAVC/PA, IVS/TOF/PA, VSD/TGA/TGA/AVC/EA/SD/MD/AD, CoA/CoA, VSD/TAPVR/CACA/TOF, AVC/MAD |
| Reference | |
|---|---|
| PMID | 22733841 |
| Year | 2013 |
| Title | Is heart transplantation for complex congenital heart disease a good option? A 25-year single centre experience. |
| Sample | ||
|---|---|---|
| Population | All | |
| Source | N/A | |
| Region | Bergamo, Italy | |
| Method | N/A | |
| Race | European | |
| Disease History | Fontan failure | |
| Treatment History | Heart transplantation | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | 85 | N/A |
| Age | 17 ± 13 years (median 15 years; range 0.2–58.5 years). | N/A |
| Gender (Male: Female) | 55:30 | N/A |
| Marker Level | N/A | N/A |
