| Factor Information | |
|---|---|
| Data ID | 2478 |
| Factor | Fetuses with two ventricles : PV/AoV |
| Description | Fetuses with two ventricles that required an intervention had lower pulmonary valve diameter Z-score (PV-Zscore)(−4.8±2.1 vs −2.6±1.1; P=0.0002) and lower pulmonary valve to aortic valve annular diameter ratio (PV/AoV) (0.53±0.15 vs 0.66±0.1; P=0.003). |
| Biomarker | YES |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | Treatment |
| Objective | lower pulmonary valve to aortic valve annular diameter ratio |
| p Value | 0.003 |
| Conclusion | Analysis of the pulmonary outflow tract and ductus arteriosus flow in the fetus with complex congenital heart disease can aid in identifying those that will require a neonatal intervention to augment pulmonary blood flow. This has important implications for the planning of delivery strategies. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 604 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/DORV/PS/UAVC, DORV, PS/UAVC, TOF/UAVC, DORV, TAPVC/DILV, PS/DORV, MS, PS |
| Reference | |
|---|---|
| PMID | 22605656 |
| Year | 2012 |
| Title | Pulmonary outflow tract obstruction in fetuses with complex congenital heart disease: predicting the need for neonatal intervention. |
| Sample | ||
|---|---|---|
| Population | fetus | |
| Source | N/A | |
| Region | Philadelphia, USA | |
| Method | Echocardiograms | |
| Race | North American | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Intervention group(Treatment) | No intervention group(Control) |
| Number | 20 | 32 |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | PV/AoV: 0.53±0.15 | PV/AoV: 0.66±0.1 |
