| Factor Information | |
|---|---|
| Data ID | 2514 |
| Factor | BMI 3 catergories (reference=BMI>25) |
| Description | N/A |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | Amiodarone therapy in adults with congenital heart disease (CHD) is associated with a significant risk of amiodarone-induced thyrotoxicosis (AIT). We developed a risk index to identify those patients being considered for amiodarone treatment who are at high risk for AIT. |
| p Value | 0.009 |
| HR | 2.286 |
| Conclusion | We derived the first model to quantify the risk for developing amiodarone-induced thyrotoxicosis(AIT) among adults with CHD. Before using it clinically to help selecting among alternative antiarrhythmic options, it needs validation in an independent population |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 22518347 |
| Year | 2012 |
| Title | A Risk Prediction Index for Amiodarone-Induced Thyrotoxicosis in Adults with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | patients' data | |
| Region | Rochester, America | |
| Method | cox proportional hazard model | |
| Race | American | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | group with AIT (amiodarone-induced thyrotoxicosis)(Treatment) | group without AIT(Control) |
| Number | 23 | 146 |
| Age | 3.51(2.7-5.2) | 2.96(3.05-4.12) |
| Gender (Male: Female) | 13:10:00.000 | 76:93 |
| Marker Level | N/A | N/A |
