| Factor Information | |
|---|---|
| Data ID | 2584 |
| Factor | association of plasma VWF:Ag with the risk of death adjusted for : age |
| Description | HR associated with an average VWF:Ag (mean of determinations performed at baseline, 30, 90, and 180 days) above the level corresponding to the 90th percentile of controls |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | We measured plasma levels of eight microvascular dysfunction markers in CHD-PAH, and tested for associations with survival. |
| p Value | 0.075 |
| HR | 4.23 |
| Conclusion | The risk of death associated with an average VWF:Ag above the level corresponding to the 90th or 95th percentile of controls was high. None of the demographic, functional or treatment-related variables listed in Table 5 had a significant association with survival during the period of the study. |
| Risk Factor | unrelated |
| CHD Type | |
|---|---|
| ID | 610 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | VSD/ASD/AVSD/PDA/AVSD/VSD, PDA/DORV/TGA, VSD/SV |
| Reference | |
|---|---|
| PMID | 22068906 |
| Year | 2011 |
| Title | Plasma von Willebrand factor as a predictor of survival in pulmonary arterial hypertension associated with congenital heart disease |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | patients' data | |
| Region | Sao Paulo, Brasil | |
| Method | multivariate analysis | |
| Race | Brazilian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | N/A | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | N/A | N/A |