Factor Information
Data ID 2584
Factor association of plasma VWF:Ag with the risk of death adjusted for : age
Description HR associated with an average VWF:Ag (mean of determinations performed at baseline, 30, 90, and 180 days) above the level corresponding to the 90th percentile of controls
Biomarker NA
Classification Z (combined factor - combined factor)
Association
Application risk assessment and prognosis
Objective We measured plasma levels of eight microvascular dysfunction markers in CHD-PAH, and tested for associations with survival.
p Value 0.075
HR 4.23
Conclusion The risk of death associated with an average VWF:Ag above the level corresponding to the 90th or 95th percentile of controls was high. None of the demographic, functional or treatment-related variables listed in Table 5 had a significant association with survival during the period of the study.
Risk Factor unrelated
CHD Type
ID 610
CHD Type isolated CHD/non-isolated CHD
CHD Subtype VSD/ASD/AVSD/PDA/AVSD/VSD, PDA/DORV/TGA, VSD/SV
Reference
PMID 22068906
Year 2011
Title Plasma von Willebrand factor as a predictor of survival in pulmonary arterial hypertension associated with congenital heart disease
Sample
Population adults
Source patients' data
Region Sao Paulo, Brasil
Method multivariate analysis
Race Brazilian
Disease History N/A
Treatment History N/A
Group N/A(Treatment) N/A(Control)
Number N/A N/A
Age N/A N/A
Gender (Male: Female) N/A N/A
Marker Level N/A N/A