Factor Information
Data ID 2693
Factor Borg dyspnea index
Description There was a significant decrease in Borg dyspnea index in the ASD group compared with baseline, but it did not reach statistical significance in the VSD and PDA groups.
Biomarker NA
Classification E10 (physiological factor - other)
Association
Application prognosis
Objective The potential effect of sildenafil on pulmonary arterial hypertension related to CHD may be associated with shunt location.
p Value 0.041
Conclusion There was a significant decrease in Borg dyspnea index in the ASD group compared with baseline, but it did not reach statistical significance in the VSD and PDA groups.
Risk Factor unknown
CHD Type
ID 484
CHD Type isolated CHD
CHD Subtype ASD/VSD/PDA
Reference
PMID 21678455
Year 2011
Title The efficacy and safety of sildenafil in patients with pulmonary arterial hypertension associated with the different types of congenital heart disease
Sample
Population adults
Source 12-week, prospective, open label, multicenter trial
Region Beijing, China
Method 12-week, prospective, open label, multicenter trial
Race Asian
Disease History N/A
Treatment History N/A
Group ASD (12 Weeks)(Treatment) ASD (Baseline)(Control)
Number 15 15
Age 32.20 ± 6.32 years 32.20 ± 6.32 years
Gender (Male: Female) 0:15 0:15
Marker Level 1.8 ± 1.0 2.6 ± 1.3