| Factor Information | |
|---|---|
| Data ID | 2761 |
| Factor | LDL-cholesterol, mmol/l |
| Description | Mean total cholesterol (4.9 vs. 4.7 mmol l-1), LDL-cholesterol (3.2 vs. 3.0 mmol l-1) and apolipoprotein B (84.0 vs. 80.0 mg dl-1) are significantly higher in case mothers than in controls. |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | We examined whether maternal lipid levels are associated with the risk of CHD offspring. |
| p Value | <0.05 |
| Conclusion | Mean total cholesterol (4.9 vs. 4.7 mmol l-1), LDL-cholesterol (3.2 vs. 3.0 mmol l-1) and apolipoprotein B (84.0 vs. 80.0 mg dl-1) are significantly higher in case mothers than in controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 21186113 |
| Year | 2012 |
| Title | A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring |
| Sample | ||
|---|---|---|
| Population | mothers of children with and without CHD | |
| Source | a case-control study | |
| Region | Rotterdam, The Netherlands | |
| Method | Demographics | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD group(Treatment) | Control group(Control) |
| Number | 229 | 320 |
| Age | 33.1 (25.3-41.5) years | 32.6 (24.5-39.8) years |
| Gender (Male: Female) | 0:229 | 0:320 |
| Marker Level | 3.2 (2.1-4.8) mmol/l | 3.0 (1.9-4.6) mmol/l |
