| Factor Information | |
|---|---|
| Data ID | 2764 |
| Factor | Apolipoprotein B/A-1 |
| Description | Furthermore, case mothers show a higher ratio of total cholesterol/HDL-cholesterol (3.5 vs. 3.3) and apolipoprotein B/apolipoprotein A-I (0.59 vs. 0.56) than controls. |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | We examined whether maternal lipid levels are associated with the risk of CHD offspring. |
| p Value | <0.01 |
| Conclusion | Furthermore, case mothers show a higher ratio of total cholesterol/HDL-cholesterol (3.5 vs. 3.3) and apolipoprotein B/apolipoprotein A-I (0.59 vs. 0.56) than controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 21186113 |
| Year | 2012 |
| Title | A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring |
| Sample | ||
|---|---|---|
| Population | mothers of children with and without CHD | |
| Source | a case-control study | |
| Region | Rotterdam, The Netherlands | |
| Method | Demographics | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD group(Treatment) | Control group(Control) |
| Number | 258 | 322 |
| Age | 33.1 (25.3-41.5) years | 32.6 (24.5-39.8) years |
| Gender (Male: Female) | 0:258 | 0:322 |
| Marker Level | 0.59 (0.38-0.84) | 0.56 (0.36-0.81) |
