Factor Information
Data ID 2765
Factor Total homocysteine, umol/l
Description Total homocysteine is higher in case mothers than in controls (10.8 vs. 10.2 mmol l-1), which confirms our previously demonstrated association in a subset of these mothers.
Biomarker NA
Classification E2 (physiological factor - biochemical index)
Association
Application prognosis
Objective We examined whether maternal lipid levels are associated with the risk of CHD offspring.
p Value <0.05
Conclusion Total homocysteine is higher in case mothers than in controls (10.8 vs. 10.2 mmol l-1), which confirms our previously demonstrated association in a subset of these mothers.
Risk Factor unknown
CHD Type
ID 148
CHD Type NA
CHD Subtype NA
Reference
PMID 21186113
Year 2012
Title A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring
Sample
Population mothers of children with and without CHD
Source a case-control study
Region Rotterdam, The Netherlands
Method Demographics
Race Europe
Disease History N/A
Treatment History N/A
Group CHD group(Treatment) Control group(Control)
Number 210 284
Age 33.1 (25.3-41.5) years 32.6 (24.5-39.8) years
Gender (Male: Female) 0:210 0:284
Marker Level 10.8 (6.9-19.6) umol/l 10.2 (6.4-16.8) umol/l