CHDRFKB

Factor Information
Data ID	2881
Factor	The mean number of risk factors
Description	On univariate analysis, twin pregnancy and BPS were significantly associated with RHF and a trend was noted for RVH. For further analysis, we defined additional risk factors as the presence of one or more of the following: twin pregnancy, CBPS, RVH, or RV systolic dysfunction.
Biomarker	NA
Classification	A10 (clinical factor - risk factor)

Association
Application	risk assessment
Objective	To determine pregnancy outcome and risk factors for adverse events in women with congenital heart disease (CHD) and residual haemodynamic right ventricular (RV) outflow tract (RVOT) lesions.
p Value	0.003
Conclusion	In those 30 pregnancies(39%) with moderate-to-severe PR at baseline, the mean number of risk factors was significantly higher in patients with symptomatic RHF (1.71 vs. 0.26 risk factors, P ¼ 0.003). Patients with moderate-tosevere PR were at risk for symptomatic RHF only if additional risk factors were present.
Risk Factor	unknown

Reference
PMID	20511325
Year	2010
Title	Pregnancy outcome in women with congenital heart disease and residual haemodynamic lesions of the right ventricular outflow tract

Sample
Population	pregnant women
Source	Data
Region	London, UK
Method	Pregnancy outcome data for women with CHD and residual RVOT lesions have been recorded since 2001.
Race	Europe
Disease History	N/A
Treatment History	isolated pulmonary valvotomy/repair including a transannular patch/an RV to pulmonary artery conduit
Group	pregnancies (39%) with moderate-to-severe PR at baseline(Treatment)	symptomatic RHF(Control)
Number	12	7
Age	27.2±7.0 years	28.7±5.4 years
Gender (Male: Female)	N/A	0:7
Marker Level	risk factor: 1.71	risk factor: 0.26