| Factor Information | |
|---|---|
| Data ID | 2886 |
| Factor | %MS (percentage media wall area) |
| Description | The percentage media wall area, percentage media wall thickness and arteriole density were significantly increased in patients associated with PH than in normal subjects (P<0.001). |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | diagnosis |
| Objective | This study aimed to examine the nature of the pulmonary arterial vessels in these selective patients. |
| p Value | <0.001 |
| Conclusion | The percentage media wall area, percentage media wall thickness and arteriole density were significantly increased in patients associated with PH than in normal subjects (P<0.001). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 635 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD, VSD/VSD/ASD/TGA, VSD/TBA |
| Reference | |
|---|---|
| PMID | 20494465 |
| Year | 2011 |
| Title | Lung biopsy findings in previously inoperable patients with severe pulmonary hypertension associated with congenital heart disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | Lung biopsy specimens | |
| Region | Beijing, China | |
| Method | All specimens were quantitatively analyzed | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | radical repair | |
| Group | Group I (patients with CHD and severe pulmonary hypertension (PH) who undergo radical repair )(Treatment) | Group II (control Group)(Control) |
| Number | 49 | 6 |
| Age | 36.5±23.8 months | 20.8±13.5 months |
| Gender (Male: Female) | 29:20 | 4:2 |
| Marker Level | 54.9±7.2% | 27.0±5.7% |