Factor Information
Data ID 2968
Factor five-year death rate in hyponatraemia patients
Description On univariate Cox survival analysis, patients with hyponatraemia had a three-fold increase in the hazard of death.
Biomarker NA
Classification A3 (clinical factor - disease & symptom)
Association
Application risk assessment
Objective prognostic implications of hyponatraemia in ACHD
p Value <0.0001
HR 3.26
Conclusion On univariate Cox survival analysis, patients with hyponatraemia had a three-fold increase in the hazard of death.
Risk Factor risk factor
CHD Type
ID 642
CHD Type isolated CHD/non-isolated CHD
CHD Subtype ASD/VSD/AVSD/AC/TOF/TGA/ACHD
Reference
PMID 19933692
Year 2010
Title Hyponatraemia: a strong predictor of mortality in adults with congenital heart disease
Sample
Population adults
Source patients' data
Region London, UK
Method univariable analysis Cox survival analysis and adjusted model
Race British
Disease History N/A
Treatment History N/A
Group ACHD with sodium <136mmol/L(Treatment) ACHD with sodium >136mmol/L(Control)
Number 34 64
Age 37.4±15.8 35.9±14.1
Gender (Male: Female) 73:83 416:432
Marker Level cumulative mortality:21.6%(hypona traemic patients) cumulative mortality:7.5%(without hyponatraemic patients)