| Factor Information | |
|---|---|
| Data ID | 2969 |
| Factor | relation between hyponatraemia and death |
| Description | When use of diuretics and previous surgical repair were used as strata in the multivariable Cox model to account for violation of the proportional hazards assumption. |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | prognostic implications of hyponatraemia in ACHD |
| p Value | <0.0001 |
| HR | 2.62 |
| Conclusion | On multivariable Cox survival model analysis, patients with hyponatraemia had a nearly three-fold increase in the hazard of death. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 642 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/VSD/AVSD/AC/TOF/TGA/ACHD |
| Reference | |
|---|---|
| PMID | 19933692 |
| Year | 2010 |
| Title | Hyponatraemia: a strong predictor of mortality in adults with congenital heart disease |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | patients' data | |
| Region | London, UK | |
| Method | multivariable Cox survival model analysis | |
| Race | British | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | ACHD with sodium <136mmol/L(Treatment) | ACHD with sodium >136mmol/L(Control) |
| Number | 156 | 848 |
| Age | 37.4±15.8 | 35.9±14.1 |
| Gender (Male: Female) | 73:83 | 416:432 |
| Marker Level | N/A | N/A |
