| Factor Information | |
|---|---|
| Data ID | 3181 |
| Factor | effects of sotalol on QTc in V5 (ms) |
| Description | N/A |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | The purpose of this study was to assess the efficacy and safety of sotalol for refractory tachyarrhythmias in patients with CHD. |
| p Value | <0.01 |
| Conclusion | Sotalol decreased all HR parameters on Holter monitoring and maximal HR and on treadmill excise tolerance testing, and prolonged QTc. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 659 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF, PA/TOF/EA/UVH/TGA/PA/ccTGA |
| Reference | |
|---|---|
| PMID | 18931451 |
| Year | 2008 |
| Title | Efficacy and safety of sotalol for refractory tachyarrhythmias in congenital heart disease |
| Sample | ||
|---|---|---|
| Population | adolescent and adult | |
| Source | patients' data | |
| Region | Suita, Japan | |
| Method | Fisher's exact test | |
| Race | Japanese | |
| Disease History | N/A | |
| Treatment History | surgery | |
| Group | before using sotalol(Treatment) | after using sotalol(Control) |
| Number | 24 | 24 |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 427±29 | 445±40 |
