| Factor Information | |
|---|---|
| Data ID | 319 |
| Factor | 6-MWD |
| Description | N/A |
| Biomarker | NA |
| Classification | C3 (lifestycle factor - exercise habit) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | PAH-CHD patients |
| p Value | 0.007 |
| Conclusion | Both therapies were associated with improvement of the physical capacity (functional class and distance walked during the 6‐minute test). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 101 |
| CHD Type | isolated CHD |
| CHD Subtype | CHD with PAH |
| Reference | |
|---|---|
| PMID | 30343508 |
| Year | 2019 |
| Title | Phosphodiesterase type 5 inhibitors improve microvascular dysfunction markers in pulmonary arterial hypertension associated with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adolescents and adults | |
| Source | data | |
| Region | Brazil, Sao Paulo | |
| Method | Student’s t test or the Mann- Whitney test | |
| Race | American | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Sildenafil group(3 months)(Treatment) | baseline(Control) |
| Number | 16 | 16 |
| Age | 10-54 years | 18-50 years |
| Gender (Male: Female) | 7:9 | 7:9 |
| Marker Level | 521(493-557) | 484(410-523) |
