| Factor Information | |
|---|---|
| Data ID | 3204 |
| Factor | Aspirin (%) |
| Description | GFR=glomerular filtration rate; |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | We studied the prevalence of renal dysfunction in adult patients with congenital heart disease (ACHD) and its relation to outcome. |
| p Value | 0.002 |
| Conclusion | Deranged physiology in adult patients with congenital heart disease is not limited to the heart but also affects the kidney. Mortality is 3-fold higher than normal in the 1 in 11 patients who have moderate or severe GFR reduction. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 661 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/VSD/AVSD/CoA/TOF/ccTGA/EA/ES/PA/other |
| Reference | |
|---|---|
| PMID | 18443238 |
| Year | 2008 |
| Title | Prevalence, Predictors, and Prognostic Value of Renal Dysfunction in Adults With Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | patients' data | |
| Region | London, United Kindom | |
| Method | pairwise comparison with boosted regression | |
| Race | British | |
| Disease History | N/A | |
| Treatment History | surgery | |
| Group | normal GFR/mild reduction GFR/moderate to severe reduction GFR(Treatment) | N/A(Control) |
| Number | Normal=549; Mild=451; Moderate to Severe=102 | N/A |
| Age | Normal=30.1±11.5; Mild=39.9±13.1; Moderate to Severe=50.4±16.1 | N/A |
| Gender (Male: Female) | Normal=30.1±11.5; Mild=39.9±13.1; Moderate to Severe=50.4±16.1 | N/A |
| Marker Level | Normal=12.8%; Mild=16.9%; Moderate to Severe=26.5% | N/A |
