| Factor Information | |
|---|---|
| Data ID | 3255 |
| Factor | S.aureus as causative organism |
| Description | N/A |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | Despite developments in preventative and medical therapy, infective endocarditis (IE) carries a high rate of mortality. Risk factors for mortality are unknown in pediatric and adult patients with congenital heart disease (CHD).The present study aimed to determine the risk factors for mortality in pediatric and adult patients with CHD using a nationwide survey in Japan. |
| p Value | <0.001 |
| OR | 8.1 |
| Conclusion | Risk factors significantly associated with outcome were age <1 year, nosocomial IE, S. aureus as the causative organism, heart failure, vegetation size >=20 mm, perioperative IE, cyanotic CHD, vegetation size >=15 mm, and previous surgery for CHD, in that order (Table 3). The site of infection was not associated with mortality (Table 3). |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 666 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | VSD/VSD, ASD/VSD, PDA/MS/AS/CoA, VSD/CoA/ccTGA/EA/DORV/TOF/ccTGA/ASD/CAT/ccTGA, VSD, PS/TS, HRV, PS/AVAS/other |
| Reference | |
|---|---|
| PMID | 18157976 |
| Year | 2007 |
| Title | Risk Factors for In-Hospital Mortality During Infective Endocarditis in Patients With Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | children and adults | |
| Source | patients' data | |
| Region | Koriyama, Japan | |
| Method | univariate regression analysis | |
| Race | Japanese | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | decreased patients with S.aureus as causative organism(Treatment) | decreased patients without S.aureus as causative organism(Control) |
| Number | N/A | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 10/39 (26%) | 4/98 (4%) |
