| Factor Information | |
|---|---|
| Data ID | 33 |
| Factor | Cell-free plasma hemoglobin levels/VIS at 0-48 hr post-CPB |
| Description | The change in cell-free plasma hemoglobin was associated with VIS less than 2hr (R2 = 0.22; p < 0.01), 2–24hr (R2 = 0.24; p < 0.01), and 24–48hr (R2 = 0.48; p < 0.001) post-CPB |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To access of cell-free plasma hemoglobin and its association with VIS. |
| p Value | <0.01 |
| Conclusion | In low-risk pediatric patients undergoing CPB for cardiac surgery, 9-HODE, 13-HODE, PHb, and WBC count increased and 9:13-HODE was associated with the ΔPHb, milrinone use, VIS, and WBC count. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 31305328 |
| Year | 2019 |
| Title | Bioactive Oxylipins in Infants and Children With Congenital Heart Disease Undergoing Pediatric Cardiopulmonary Bypass. |
| Sample | ||
|---|---|---|
| Population | Infants and Children | |
| Source | plasma | |
| Region | Pittsburgh, USA | |
| Method | Plasma was collected at the start and end of cardiopulmonary bypass in 34 patients. 9-hydroxyoctadecadienoic acid, 13-hydroxyoctadecadienoic acid, plasma hemoglobin, and WBC increased. | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | Pediatric Cardiopulmonary Bypass, cardiac surgery | |
| Group | start CPB(Treatment) | N/A(Control) |
| Number | 34 (all patients) | N/A |
| Age | 2.5 (0.6–12.0) years | N/A |
| Gender (Male: Female) | 18:16 | N/A |
| Marker Level | N/A(start CPB) | N/A |
