| Factor Information | |
|---|---|
| Data ID | 3371 |
| Factor | Sotalol (%) |
| Description | N/A |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | To assess the prognostic value of heart rate response to exercise in adult congenital heart disease (ACHD) patients. |
| p Value | 0.02 |
| Conclusion | An abnormal heart rate response to exercise identifies ACHD patients with a higher risk of mortality in the midterm, even after accounting for antiarrhythmic medication and exercise capacity. Heart rate reserve is a simple and inexpensive way to identify ACHD patients at higher mortality risk. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 675 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/ccTGA/CoA/other/EA/ES/TOF/VSD |
| Reference | |
|---|---|
| PMID | 16979014 |
| Year | 2006 |
| Title | Heart Rate Response During Exercise Predicts Survival in Adults With Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | patients' data | |
| Region | London, United Kindom | |
| Method | chi-square test | |
| Race | British | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | patients achieving to reach a chronotropic index of at least 80%(Treatment) | patients failing to reach a chronotropic index of at least 80%(Control) |
| Number | 453 | 274 |
| Age | 33±13 yrs | 33±13 yrs |
| Gender (Male: Female) | 213:240 | 167:107 |
| Marker Level | 0.05 | 0.02 |
