| Factor Information | |
|---|---|
| Data ID | 34 |
| Factor | C-index of CHDFI |
| Description | The C-index of the CHDFI was significantly higher than the C-index of the Disease Severity Index for all-cause and cardiac mortality. |
| Biomarker | NA |
| Classification | A6 (clinical factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | predicting all-cause, 15-year mortality in adults with CHD |
| p Value | <0.01 |
| Conclusion | The CHDFI demonstrated the highest discrimination ability and emphasizes the importance to integrate both anatomic and physiological variables to predict long-term mortality. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 399 |
| CHD Type | isolated CHD |
| CHD Subtype | TOF/VSD/CoA/AVS/PVS/TGA/AVD/ASD/MI/UVH/DORV/ccTGA/EA of the tricuspid valve/AVI/ASD/other |
| Reference | |
|---|---|
| PMID | 31292090 |
| Year | 2019 |
| Title | Predicting 15-Year Mortality in Adults With Congenital Heart Disease Using Disease Severity and Functional Indices. |
| Sample | ||
|---|---|---|
| Population | youth, adults | |
| Source | Visited & Collect | |
| Region | Leuven, Belgium | |
| Method | Harrell’s concordance statistics index (C-index) was calculated for each classification system through Cox hazard regression analysis | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD(Treatment) | N/A(Control) |
| Number | 629 | 629 |
| Age | ＞15 years(median:24 years) | ＞15 years(median:24 years) |
| Gender (Male: Female) | 378:251 | 378:251 |
| Marker Level | 0.76( CHDFI) | Bethesda classification =0.67; NYHA=0.65; ability index=0.64; Disease Severity Index=0.65 |
