| Factor Information | |
|---|---|
| Data ID | 3450 |
| Factor | antibiotic treatment (third-generation cephalosporins) |
| Description | N/A |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | risk assessment and prognosis |
| Objective | To identify the main risk factors for the acquisition of candidemia in children with congenital heart disease (CHD) in order to improve the clinical management of these patients. |
| p Value | <0.01 |
| OR | 37.9 |
| Conclusion | Patients with CHD who have a high TISS score 1 week after PICU admission and patients who have received prolonged antibiotic therapy should be considered at high risk for candidemia. Our results suggest that shorter courses of antibiotic therapy, routine surveillance culture for Candida species, and initiation of preemptive or empirical antifungal treatment could help in the clinical management of these patients. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 16755476 |
| Year | 2006 |
| Title | Risk Factors for Candidemia in Pediatric Patients With Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | pediatric | |
| Source | patients' data | |
| Region | Madrid, Spain | |
| Method | univariate analyses | |
| Race | Spanish | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | pediatric patient with CHD and candidemia admitted to PICU(Treatment) | pediatric patients with CHD and without candidemia admitted to PICU(Control) |
| Number | 28 | 47 |
| Age | 12.5±32.0 months | 38.0±48.0 months |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 26 (93%) | 12 (25%) |
