Factor Information
Data ID 3459
Factor NT-pro-BNP (pg/mL)
Description NT-pro brain natriuretic peptide
Biomarker NA
Classification E2 (physiological factor - biochemical index)
Association
Application risk assessment and prognosis
Objective The purpose of our study was to evaluate if cardiac pacing is a risk factor of heart failure during longtime follow-up of grown ups with congenital heart disease (GUCH).
p Value <0.0001
Conclusion Pacemaker implantation may be associated with heart failure during longtime follow-up of GUCH indicated by significantly elevated BNP levels and decreased VO2max. Possible explanations are prolongation of QRS complex duration, decreased maximal heart rates during exercise, and dilatation of the right ventricle.
Risk Factor unknown
CHD Type
ID 677
CHD Type isolated CHD/non-isolated CHD
CHD Subtype TOF/D-TGA/SV/LTRS/AVD, PVD, CoA/other
Reference
PMID 16650267
Year 2006
Title Pacemaker Implantation as a Risk Factor for Heart Failure in Young Adults with Congenital Heart Disease
Sample
Population young adults
Source patients' data
Region Gottingen, Germany
Method student t-test
Race German
Disease History N/A
Treatment History N/A
Group patients with pacemaker(Treatment) patients without pacemaker(Control)
Number 39 307
Age 28.1±1.3 yrs 26.3±0.5 yrs
Gender (Male: Female) 26:13 N/A
Marker Level 448.2±76.8 123.8±9.7