Factor Information
Data ID 3738
Factor Correlation between Ross score and β2-receptor gene expression
Description the Ross score showed a significant correlation with β1-receptor gene expression (r=-0.47, p=0.015).
Biomarker NA
Classification Z (combined factor - combined factor)
Association
Application prognosis
Objective β-Receptor Downregulation in Congenital Heart Disease: A Risk Factor for Complications After Surgical Repair?
p Value 0.015
Conclusion β-Receptor downregulation due to congestive heart failure has an impact on the postoperative course in children with congenital disease and depends on heart failure therapy.
Risk Factor unknown
CHD Type
ID 696
CHD Type isolated CHD/non-isolated CHD
CHD Subtype AVSD/VSD/PA/RV-PA-Cd/TOF/PI/DILV/L-TGA/PAB/TA/AP window/DILV, L-TGA/DORV, SPS/MA/AVSD, CoA, PAB/TA, CoA, PAB
Reference
PMID 11845882
Year 2002
Title Beta-receptor downregulation in congenital heart disease: a risk factor for complications after surgical repair?
Sample
Population All
Source right atrium during cardiac surgery
Region Gottingen, Germany
Method Myocardial biopsies/real-time polymerase chain reaction with fluorescence- labeled products
Race European
Disease History N/A
Treatment History Biventricular repair/Glenn op/TCPC/PAB/DKS/CoA resection
Group N/A(Treatment) N/A(Control)
Number 17 9
Age N/A N/A
Gender (Male: Female) N/A N/A
Marker Level N/A N/A