| Factor Information | |
|---|---|
| Data ID | 3775 |
| Factor | an increasing lactate level over time |
| Description | correlation between lactate level and death or the requirement for ECMO support |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To determine whether a change in lactate level was predictive of a poor outcome defined as death within the first 72 hours or the need for extracorporeal membrane oxygenation. |
| p Value | <0.001 |
| Conclusion | In contrast, an increasing lactate level over time (a change in lactate level of 0.75 mmol/L per hour or more) was associated with death or the requirement for ECMO support (P < .0001) and predicted a poor outcome outcome with an 89% sensitivity value, a 100% specificity value, and a 100% positive predictive value. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 705 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | HLHS/DILV, HRV, SAS, HAA/IAA/IAA, VSD, AS/AVSD, HLV, TAPVR/IAA, VSD, SAS/IAA, VSD, SAS/CoA, VSD, AS/CoA, VSD/D-TGA/D-TGA, VSD, CoA/DORV, D-MGA, CoA/TA, D-MGA, HRV/L-TGA, PA, CAVV, TAPVR/TOF, APV |
| Reference | |
|---|---|
| PMID | 10884658 |
| Year | 2000 |
| Title | Serial blood lactate measurements predict early outcome after neonatal repair or palliation for complex congenital heart disease |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | patients' blood | |
| Region | Michigan, USA | |
| Method | Multivariable logistic modeling | |
| Race | American | |
| Disease History | N/A | |
| Treatment History | Modified Norwood/cardiac repair operation | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | N/A | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | N/A | N/A |
