Factor Information
Data ID 3811
Factor Peak E/A (Postoperative diastolic parameters, day 1 to 3)
Description The E to A wave ratios for both peak velocity and velocity time integral were significantly elevated in the group with mid-diastolic flow reversal.
Biomarker YES
Classification E10 (physiological factor - other)
Association
Application prognosis and risk assessment
Objective To determine whether mid-diastolic flow reversal predicts outcome in patients undergoing repair or palliation of neonatal congenital heart disease
p Value <0.001
Conclusion The E to A wave ratios for both peak velocity and velocity time integral were significantly elevated in the group with mid-diastolic flow reversal.
Risk Factor unknown
CHD Type
ID 711
CHD Type isolated CHD
CHD Subtype TGA/CoA/IAA/AS
Reference
PMID 9842023
Year 1998
Title Abnormal left ventricular filling after neonatal repair of congenital heart disease: Association with increased mortality and morbidity
Sample
Population neonates
Source cohort
Region NC, USA
Method echocardiograms and medical records
Race North America
Disease History N/A
Treatment History N/A
Group MDFR (patients with mid-diastolic flow reversal)(Treatment) No MDFR (patients without mid-diastolic flow reversal)(Control)
Number 21 19
Age 2 to 21 days (mean 11.3 ± 5.4 days) 2 to 21 days (mean 11.3 ± 5.4 days)
Gender (Male: Female) N/A N/A
Marker Level 2.89 ± 1.11 1.37 ± 0.34