| Factor Information | |
|---|---|
| Data ID | 3843 |
| Factor | Plasma TXB2 levels |
| Description | Plasma TXB2 levels were measured by radioimmunoassay. Plasma TXB2 levels in the three groups (control, Rp < or = 10, and Rp > 10) were significantly different (P < .005); the TXB2 levels in the Rp < or = 10 group were significantly higher than the others. |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | In the present study, we measured the plasma TXB2 concentration to evaluate platelet activation in patients with pulmonary hypertension and congenital heart disease. |
| p Value | <0.005 |
| Conclusion | Plasma TXB2 levels were measured by radioimmunoassay. Plasma TXB2 levels in the three groups (control, Rp < or = 10, and Rp > 10) were significantly different (P < .005); the TXB2 levels in the Rp < or = 10 group were significantly higher than the others. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 715 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | VSD/VSD, ASD/VSD, CoA/VSD, PDA/AS/PDA/DORV/CAVC/TOF, PA/ECD, PDA/EA/other |
| Reference | |
|---|---|
| PMID | 7994842 |
| Year | 1994 |
| Title | Plasma thromboxane B2 concentration in pulmonary hypertension associated with congenital heart disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | Blood | |
| Region | Osaka, Japan | |
| Method | Informed consent to the study was obtained from the patients or their parents | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | cardiac catheterization | |
| Group | Rp≤10 group(Treatment) | Control group(Control) |
| Number | 59 | 16 |
| Age | 3.7±6.4 years 0.9±0.8 years | 8.6±6.2 years |
| Gender (Male: Female) | 12:7 | 7:9 |
| Marker Level | 337.9±424.8 pg/mL | 70.7±35.4 pg/mL |
