CHDRFKB

Factor Information
Data ID	3891
Factor	Least-Concentration to the Systemic-Recirculation concentration Ratios (CL/CR) Obtained From Arterial Dilution Curve
Description	The most applications of arterial indicator-dilution technics is their use for the detection, localization and quantitation of right-to-left shunts.
Biomarker	NA
Classification	E10 (physiological factor - other)

Association
Application	diagnosis
Objective	To access the applications of arterial indicator-dilution technics in their use for the detection, localization and quantitation of right-to-left shunts.
Conclusion	1.The technics have a high degree of safety. 2.The sensitivity of the technics for the detection and localization of right-to-left and left-to-right shunts is much superior to that of the conventional blood-gas methods. 3. Quantitative determinations of systemic and pulmonary blood flow and intrathoracic shunts by indicator-dilution methods can be made simultaneously over periods of less than 1 minute and they are independent of foreign (anesthetic) gases in the blood. 4. The technics are versatile and can be extremely useful either for the detection and diagnosis of minimal, relatively simple defects or for the elucidation of the extremely complex types of congenital malformations. 5. The information obtained is of both a qualitative and a quantitative nature; that is, the nature and location of defects can
Risk Factor	unknown

Reference
PMID	14008164
Year	1962
Title	Diagnostic applications of indicator-dilution technics in congenital heart disease.

Sample
Population	N/A
Source	patients
Region	Minnesota, America
Method	Arterial Dilution Curve
Race	American
Disease History	N/A
Treatment History	N/A
Group	patients with left-to-right shunts of 35% or less(Treatment)	healthy subjects(Control)
Number	35	23
Age	N/A	N/A
Gender (Male: Female)	N/A	N/A
Marker Level	>1.0(0.9->1.0)	0.42(0.26-0.60)