| Factor Information | |
|---|---|
| Data ID | 3980 |
| Factor | Red blood cell folate(ng/mL), median (IQR) |
| Description | the median RBC folate levels were 247.0 ng/mL in preconception women and 417.4 ng/mL in early-pregnancy women. |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To investigate the associations of parental periconceptional nutritional factors with CHD. |
| Conclusion | 20.0% of preconceptional participants and 44.9% of pregnant participants had a folate level of >400 ng/mL, which was suggested as the optimal level for preventing neural tube development defects. These results suggest that effort is urgently needed to improve folic acid supplementation in the preparing-for pregnancy population, especially before pregnancy. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 31767384 |
| Year | 2019 |
| Title | Risk of coronary artery disease in adults with congenital heart disease: A comparison with the general population |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | blood | |
| Region | Shanghai, China | |
| Method | using electrochemiluminescence assays (ARCHITECT i2000SR Analyzer; Abbott Laboratories, USA) | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | preconception women(Treatment) | early pregnant women(Control) |
| Number | 570 | 587 |
| Age | 29.9±3.9 years | 29.9±4.0 years |
| Gender (Male: Female) | 0:570 | 0:587 |
| Marker Level | 247.0 (184.8–340.5)ng/mL | 417.4 (308.6–544.2)ng/mL |
