| Factor Information | |
|---|---|
| Data ID | 3997 |
| Factor | maternal upper respiratory tract infection/ influenza during early pregnancy with simple CHD in offspring |
| Description | Maternal upper respiratory tract infection/influenza during early pregnancy, compared to controls, could increase the risk of simple and complex CHD by 2.43 (OR = 3.43, 95% CI: 2.12–5.54) and 1.43 times (OR = 2.43, 95% CI: 1.54– 4.45), respectively. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | To ascertain if maternal upper respiratory tract infection/ influenza during early pregnancy was related to an increased risk of CHD. |
| p Value | <0.001 |
| OR | 3.4 |
| Conclusion | Maternal upper respiratory tract infection/influenza during early pregnancy was a significant risk factor for both simple and complex CHD in univariate regression models |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 33 |
| CHD Type | isolated CHD |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 31791237 |
| Year | 2019 |
| Title | Associations of maternal upper respiratory tract infection/influenza during early pregnancy with congenital heart disease in offspring: evidence from a case-control study and meta-analysis |
| Sample | ||
|---|---|---|
| Population | adults | |
| Source | maternal patients | |
| Region | Shanghai, China | |
| Method | Model Ι: adjusted for maternal ethic, maternal age at delivery, maternal education, marital status, residence, maternal prepregnancy obesity, multiple births, infant gender, and family history of CHD; Model II:Model II: based on Model Ι, further adjusted for prepregnancy diabetes/hypertension, folic acid use, and smoking/drinking | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | simple CHD(Treatment) | controls(Control) |
| Number | 262 | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | N/A | N/A |
