| Factor Information | |
|---|---|
| Data ID | 401 |
| Factor | NYHA class |
| Description | The combination of multiple risk predictors into a tool that provides clinically useful risk predictions is most relevant. |
| Biomarker | NA |
| Classification | A6 (clinical factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To develop and validate a clinically useful risk prediction tool for patients with adult congenital heart disease (ACHD). |
| p Value | 0.026 |
| OR | 1.74 |
| Conclusion | The proposed ACHD risk score combines six readily available clinical characteristics and NT-proBNP. This tool is easy to use and can aid in distinguishing high- and low-risk patients, which could further streamline counselling, location of care, and treatment in ACHD. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 446 |
| CHD Type | isolated CHD |
| CHD Subtype | AS/AC/TOF/EA/AVSD/ccTGA/CHD with PAH/FUVH |
| Reference | |
|---|---|
| PMID | 30172474 |
| Year | 2019 |
| Title | Development and validation of a risk prediction model in patients with adult congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | a prospective cohort and a retrospective cohort | |
| Region | Rotterdam,the Netherlands | |
| Method | final prediction model | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Derivation cohort(Treatment) | validation cohort(Control) |
| Number | 602 | 402 |
| Age | 32.5 [24.7-41.2] years | 28.3 [22.5-36.2] years |
| Gender (Male: Female) | 348:256 | 206:196 |
| Marker Level | 602 | 402 |
