| Factor Information | |
|---|---|
| Data ID | 4028 |
| Factor | GDF-15(Growth differentiation factor 15)(pg/ml) |
| Description | Infra-tricuspid shunt group showed significantly higher levels of GDF 15 than supra-tricuspid shunt group |
| Biomarker | YES |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To compare different clinical/hemodynamic parameters between infra-tricuspid shunt group and supra tricuspid shunt group. |
| p Value | <0.0001 |
| Conclusion | Infra-tricuspid shunt group showed significantly higher levels of GDF 15 than supra-tricuspid shunt group |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 746 |
| CHD Type | isolated CHD |
| CHD Subtype | PDA/VSD/DORV/ASD/p-AVSD/PAPVR |
| Reference | |
|---|---|
| PMID | 31883956 |
| Year | 2020 |
| Title | Growth differentiation factor 15 as a useful biomarker of heart failure in young patients with unrepaired congenital heart disease of left to right shunt. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Kurume, Japan | |
| Method | Quantikine ELISA Kit | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | underwent cardiac catheterization | |
| Group | infra-tricuspid shunt(Treatment) | supra-tricuspid shunt(Control) |
| Number | 26 | 42 |
| Age | 12.5 (1–114) months | 86 (5–173) months |
| Gender (Male: Female) | 9:17 | 20:22 |
| Marker Level | 400.9 (101.9–1116.7)(pg/ml) | 170.8 (13.6–530.6)(pg/ml) |
