| Factor Information | |
|---|---|
| Data ID | 4039 |
| Factor | Ln(log transformed) NT-pro BNP |
| Description | GDF 15 levels showed significantly positive correlation with the modified Ross score (r = 0.657), mean PAp (r = 0.497), OER (r = 0.437), and Ln NT-pro BNP (r = 0.429) |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To access the correlation between GDF 15 and the modified Ross score, mean pulmonary artery pressure, oxygen extraction rate (OER), and Ln NT-pro-BNP, with age, oxygen delivery and its components, and estimated glomerular filtration rate (eGFR). |
| p Value | <0.0001 |
| Conclusion | GDF 15 significantly positively correlated with the modified Ross score, mean pulmonary artery pressure, oxygen extraction rate (OER), and Ln NT-pro-BNP, but negatively correlated with age, oxygen delivery and its components, and estimated glomerular filtration rate (eGFR). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 746 |
| CHD Type | isolated CHD |
| CHD Subtype | PDA/VSD/DORV/ASD/p-AVSD/PAPVR |
| Reference | |
|---|---|
| PMID | 31883956 |
| Year | 2020 |
| Title | Growth differentiation factor 15 as a useful biomarker of heart failure in young patients with unrepaired congenital heart disease of left to right shunt. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Kurume, Japan | |
| Method | Correlations between GDF 15 levels and variables were evaluated using the Spearman rank correlation coefficient | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | underwent cardiac catheterization | |
| Group | all patients(Treatment) | N/A(Control) |
| Number | 69 | N/A |
| Age | 71 (1–173) months | N/A |
| Gender (Male: Female) | 30:39 | N/A |
| Marker Level | R= 0.429(correlation between GDF 15 and Ln NT-pro BNP) | N/A |
