| Factor Information | |
|---|---|
| Data ID | 4057 |
| Factor | correlation between PASP(pulmonary artery systolic pressure ) and miR-204 expression in all CHD group |
| Description | There was also a negative correlation between plasma miR-204 expression and PASP in all 52 children patients (r=–0.887, P<0.001). |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | To evaluate correlation between PASP(pulmonary artery systolic pressure ) and miR-204 expression in all CHD patients. |
| p Value | <0.001 |
| Conclusion | In the mild PH and severe PH groups, plasma miR-204 expression was negatively correlated with PASP. In all 52 cases, plasma miR-204 expression was negatively cor- related with PASP, suggesting miR-204 may be involved in PH development, and miR-204 expression may be an indicator of PH severity. |
| Risk Factor | unrelated |
| CHD Type | |
|---|---|
| ID | 747 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | VSD/ASD/VSD, ASD/PDA/VSD, PDA/ASD, PDA |
| Reference | |
|---|---|
| PMID | 31887731 |
| Year | 2020 |
| Title | MicroRNA-204 as an Indicator of Severity of Pulmonary Hypertension in Children with Congenital Heart Disease Complicated with Pulmonary Hypertension |
| Sample | ||
|---|---|---|
| Population | infants/children | |
| Source | patients | |
| Region | Guizhou, China | |
| Method | The single-factor analysis of variance (one-way ANOVA) method was used in multi-group compari- sons, and pairwise comparisons of multi-groups/mean values were conducted using the LSD-t test | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | treated with conventional corrective sur- gery, combined intravenous and inhalation anesthesia, and cardiopulmonary bypass (CPB) and equipment | |
| Group | all CHD(Treatment) | N/A(Control) |
| Number | 52 | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | 21:31 | N/A |
| Marker Level | r=–0.887 | N/A |
