| Factor Information | |
|---|---|
| Data ID | 407 |
| Factor | Abnormal background pattern (BGP), 12-48 h after surgery |
| Description | aEEG is derived from (standard) electroencephalography (EEG) and has multiple characteristics for the assessment of brain activity. |
| Biomarker | YES |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To study perioperative amplitude-integrated electroencephalography (aEEG) as an early marker for new brain injury in neonates requiring cardiac surgery for critical congenital heart disease (CHD). |
| p Value | 0.02 |
| Conclusion | Abnormal brain activity is an early, bedside marker of new brain injury in neonates undergoing cardiac surgery. Not only ictal discharges, but also abnormal BGP, should be considered a clear sign of underlying brain pathology. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 447 |
| CHD Type | NA |
| CHD Subtype | BVP/BVP-AAO/SV |
| Reference | |
|---|---|
| PMID | 30144931 |
| Year | 2018 |
| Title | Amplitude-Integrated Electroencephalography for Early Recognition of Brain Injury in Neonates with Critical Congenital Heart Disease. |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | retrospective observational cohort study | |
| Region | Utrecht,The Netherlands | |
| Method | reviewed | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | neonatal surgery | |
| Group | neonates with new brain injury(Treatment) | neonates without new brain injury(Control) |
| Number | 10(total:43) | 1 (total:30) |
| Age | Gestational age: 39.1 ± 1.2 | Gestational age: 39.1 ± 1.2 |
| Gender (Male: Female) | 59:19 | 59:19 |
| Marker Level | 0.23 | 0.03 |
