| Factor Information | |
|---|---|
| Data ID | 4117 |
| Factor | Pregestational Diabetes |
| Description | Pregestational Diabetes was strongly associated with CHD (OR 4.04, 95%CI 1.00–16.28) though infrequent (1.7% of cases) |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | To investigate the role of maternal environmental factors in the aetiology of CHD. |
| OR | 4.04 |
| Conclusion | Risk of CHD was associated with low maternal education (OR adjusted for confounders 1.59; 95% [CI], 1.02–2.49), pregestational diabetes(OR 4.04; 95% CI (1.00–16.28), self-reported maternal clotting disorders (adjusted OR 8.55, 95%CI (1.51–48.44), prescriptions for the anticlotting medication enoxaparin (adjOR 3.22, 95%CI (1.01–10.22) and self-reported vaginal infections (adjOR 1.69, 95%CI (1.01–2.80). |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 749 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | anomalies of the venous return/ASD/AVSD, OPD/AVC/HLHS/VSD/TOF, TGA/CoA/CACA |
| Reference | |
|---|---|
| PMID | 32092068 |
| Year | 2020 |
| Title | Risk factors for congenital heart disease: The Baby Hearts Study, a population-based case-control study |
| Sample | ||
|---|---|---|
| Population | adults(mother of CHD offspring) | |
| Source | mother of CHD offspring | |
| Region | Belfast,Northern Ireland, United Kingdom | |
| Method | univariable analysis | |
| Race | Eupopean | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD cases(Treatment) | controls(Control) |
| Number | 4 | 4 |
| Age | N/A | N/A |
| Gender (Male: Female) | female | female |
| Marker Level | 4(1.65%) | 4(0.41%) |
