Factor Information
Data ID 4180
Factor brain volumn
Description Brain volumes show significantly slower growth in ECMO infants compared with controls.
Biomarker NA
Classification E11 (physiological factor - physical sign)
Association
Application risk assessment
Objective To compare brain volumes between pre- and postoperative brain MRI in the infants receiving extracorporeal membrane oxygenation compared with those who did not require ECMO.
p Value 0.007
Conclusion Brain volumes show significantly slower growth in ECMO infants compared with controls.
Risk Factor unknown
CHD Type
ID 750
CHD Type isolated CHD/non-isolated CHD
CHD Subtype HLHS/SV/TGA, DORV/TGA, IVS/TGA, VSD
Reference
PMID 32195905
Year 2020
Title Decreased Brain Volumes and Infants With Congenital Heart Disease Undergoing Venoarterial Extracorporeal Membrane Oxygenation
Sample
Population infants
Source patients
Region Toronto, Canada
Method Prospective and single-centered study;Kruskal-Wallis test
Race North American
Disease History N/A
Treatment History ECMO(extracorporeal membrane oxygenation)
Group ECMO(Treatment) N/A(Control)
Number 28 81
Age gestational age:39.0 (38.2–39.4)weeks gestational age:39.1 (38.6–40.0)weeks
Gender (Male: Female) 16:12 57:34
Marker Level βECMO × age at scan = –7.03 N/A