| Factor Information | |
|---|---|
| Data ID | 4181 |
| Factor | brain volumn |
| Description | The slowest rate of change in brain volumes is evident in infants receiving multiple ECMO runs than that single ECMO. |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | To compare brain volumes between pre- and postoperative brain MRI in the infants receiving extracorporeal membrane oxygenation compared with those who did not require ECMO. |
| p Value | 0.012 |
| Conclusion | The slowest rate of change in brain volumes is evident in infants receiving multiple ECMO runs than that single ECMO. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 750 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | HLHS/SV/TGA, DORV/TGA, IVS/TGA, VSD |
| Reference | |
|---|---|
| PMID | 32195905 |
| Year | 2020 |
| Title | Decreased Brain Volumes and Infants With Congenital Heart Disease Undergoing Venoarterial Extracorporeal Membrane Oxygenation |
| Sample | ||
|---|---|---|
| Population | infants | |
| Source | patients | |
| Region | Toronto, Canada | |
| Method | Prospective and single-centered study;Kruskal-Wallis test | |
| Race | North American | |
| Disease History | N/A | |
| Treatment History | ECMO(extracorporeal membrane oxygenation) | |
| Group | received ECMO 2-4 times(Treatment) | received ECMO once(Control) |
| Number | 28 | 81 |
| Age | gestational age:39.0 (38.2–39.4)weeks | gestational age:39.1 (38.6–40.0)weeks |
| Gender (Male: Female) | 16:12 | 57:34 |
| Marker Level | βmultiple ECMO × age at scan = –6.54 | βsingle ECMO × age at scan = –1.67 |
