| Factor Information | |
|---|---|
| Data ID | 4197 |
| Factor | Cardiopulmonary bypass time(min) |
| Description | ACE I/D angiotensin-converting enzyme insertion/deletion |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To test the hypothesis that the angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism associates with postoperative JET. |
| p Value | 0.01 |
| Conclusion | The common ACE deletion polymorphism is associated with a greater than 2-fold increase in the odds of developing JET in children undergoing surgical repair of AVSD, TOR, VSD or the Norwood and arterial switch procedures. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 751 |
| CHD Type | isolated CHD |
| CHD Subtype | AVSD/TOF/VSD |
| Reference | |
|---|---|
| PMID | 21740877 |
| Year | 2011 |
| Title | A genetic contribution to risk for postoperative junctional ectopic tachycardia in children undergoing surgery for congenital heart disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | patients | |
| Region | Nashville, USA | |
| Method | Taqman PCR | |
| Race | American | |
| Disease History | NA | |
| Treatment History | surgical repair | |
| Group | with JET(Treatment) | without JET(Control) |
| Number | 36 | 138 |
| Age | 96.5 (3–229) days | 157 (1–4262) days |
| Gender (Male: Female) | NA | NA |
| Marker Level | 141 (57–263) | 111 (53–404) |
