| Factor Information | |
|---|---|
| Data ID | 4223 |
| Factor | Factors associated with CPR z score: CHD diagnosis |
| Description | adjusted |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To determine the impact of damaging genetic variation in proangiogenic pathways on placental function, complications of pregnancy, fetal growth, and clinical outcomes in pregnancies with CHD. |
| p Value | 0.0495 |
| Conclusion | There was a significant trend toward reduced CPR z score in HLHS infants than those in other CHD patients both in univariate and multivariable analysis. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 752 |
| CHD Type | isolated CHD |
| CHD Subtype | HLHS/IAA/TGA/TOF/other |
| Reference | |
|---|---|
| PMID | 31227283 |
| Year | 2019 |
| Title | Damaging Variants in Proangiogenic Genes Impair Growth in Fetuses with Cardiac Defects |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | patients | |
| Region | Philadelphia, USA | |
| Method | multivariable analysis | |
| Race | American | |
| Disease History | NA | |
| Treatment History | surgical repair | |
| Group | HLHS(Treatment) | other CHD(Control) |
| Number | 50 | 50 |
| Age | NA | NA |
| Gender (Male: Female) | NA | NA |
| Marker Level | -1.61 ± 0.31 | -0.85 ± 0.22 |
