| Factor Information | |
|---|---|
| Data ID | 4225 |
| Factor | Maternal vitamin D status: Deficient |
| Description | NA |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | To access the association between maternal vitamin D status and the offsrping of CHD. |
| p Value | 0.007 |
| Conclusion | There was a significant decrease in maternal vitamin D level (P=0.002) and a significant increase in maternal vitamin D deficient status (P=0.007) among cases when compared to controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 753 |
| CHD Type | isolated CHD |
| CHD Subtype | VSD/ASD/PDA/TGA/TOF/TAS/HLHS/DORV |
| Reference | |
|---|---|
| PMID | 31194013 |
| Year | 2018 |
| Title | Maternal vitamin D level and vitamin D receptor gene polymorphism as a risk factor for congenital heart diseases in offspring; An Egyptian case-control study |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | Peripheral blood of patients | |
| Region | Zagazig, Egypt | |
| Method | ELISA, RFLP PCR assay | |
| Race | African | |
| Disease History | Previous CHD in sibilings with 20% of cases and 4% in controls | |
| Treatment History | NA | |
| Group | CHD neonates(Treatment) | healthy controls(Control) |
| Number | 24 | 8 |
| Age | 28(20-35) years | 28(20-35) years |
| Gender (Male: Female) | 00:24:00.000 | 00:08:00.000 |
| Marker Level | 0.48 | 0.16 |
