| Factor Information | |
|---|---|
| Data ID | 439 |
| Factor | Mean platelet volume (MPV) |
| Description | Mean platelet volume (MPV), platecrit, and platelet distribution width (PDW) are markers of platelet activation. Previous studies have found that platelet activation occurs in patients with pulmonary arterial hypertension. |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | diagnosis and prognosis |
| Objective | investigate the value of platelet indices with clinical and hemodynamic indicators predicting the disease severity and survival in children with APAH-CHD. |
| p Value | <0.05 |
| Conclusion | Our results showed that MPV, platecrit and PDW were increased in children with APAH-CHD. They might give clue about disease severity. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 452 |
| CHD Type | NA |
| CHD Subtype | CHD with PAH |
| Reference | |
|---|---|
| PMID | 30019380 |
| Year | 2018 |
| Title | Platelet activation markers in children with congenital heart disease associated with pulmonary arterial hypertension. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | a nested case-control study | |
| Region | Izmir,Turkey | |
| Method | Clinical and hemodynamic data were collected. | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | right heart catheterization | |
| Group | APAH-CHD who died(Treatment) | APAH-CHD survived(Control) |
| Number | 11 | 26 |
| Age | 93.90±81.94months | 128.33±65.45months |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 12.10 femoliter [fL; 8.20-12.50] | 8.70 fL [6.40-9.70] |
