| Factor Information | |
|---|---|
| Data ID | 453 |
| Factor | vasoactive-inotropic score (VIS) |
| Description | IS and VIS have been estimated in the immediate post-operativeperiod and during LCOS development and have been associated with the cardiac markers above mentioned predictors of LCOS in the paediatric population. |
| Biomarker | NA |
| Classification | A6 (clinical factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To determine the predictive value of the inotropic score (IS) and vasoactive-inotropic score (VIS) in low cardiac output syndrome (LCOS) in children after congenital heart disease surgery involving cardiopulmonary bypass (CPB). |
| p Value | 0.007 |
| OR | 6.04 |
| Conclusion | The VIS score at 2h post-CPB was identified as an independent early predictor of LCOS. This predictive value was not increased when associated with LCOS cardiac biomarkers. The VIS score was more useful than IS post-CPB in making early therapeutic decisions in clinical practice post-CPB. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 455 |
| CHD Type | isolated CHD |
| CHD Subtype | TOF/AVC/CAT/HLHS/CoA, IAA/MR, AOR/PA/TAPVC/TGA/VSD/ASD/other |
| Reference | |
|---|---|
| PMID | 29910113 |
| Year | 2019 |
| Title | Evaluation of the vasoactive-inotropic score,mid-regional pro-adrenomedullin and cardiac troponin Ias predictors of low cardiac output syndromein children after congenital heart disease surgery. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Barcelona,Spain | |
| Method | Baseline blood samples were collected from a central venouscatheter prior to corrective surgery and at 2, 12, 24, and 48 hpost-CPB. | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | CHD surgery requiring CPB | |
| Group | LCOS group(Treatment) | non-LCOS group(Control) |
| Number | 33 | 82 |
| Age | 39.84 ± 52.43 months | 39.84 ± 52.43 months |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | >25 | <20 |
