| Factor Information | |
|---|---|
| Data ID | 46 |
| Factor | poor sleep |
| Description | The prevalence of poor sleep in mother was significantly higher in cases with severe CHD than that in controls. |
| Biomarker | NA |
| Classification | C5 (lifestycle factor - routine) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To access if poor maternal sleep around periconceptional period is an independent risk factor for CHD. |
| p Value | 0.019 |
| Conclusion | The prevalence of poor sleep in mother was significantly higher in cases with severe CHD than that in controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 401 |
| CHD Type | isolated CHD |
| CHD Subtype | DORV/TGA/AVSD/TOF/HLHS/SV/TAPVR/TS |
| Reference | |
|---|---|
| PMID | 31206252 |
| Year | 2019 |
| Title | Exploring associations of maternal sleep during periconceptional period with congenital heart disease in offspring |
| Sample | ||
|---|---|---|
| Population | mothers:adults;cases: children | |
| Source | questionnaires | |
| Region | Shanghai, China | |
| Method | Periconceptional Behaviors and Environmental Exposure Questionnaire (PBEQ). | |
| Race | Asian | |
| Disease History | 0.5-1.1% with prepregnancy diabetes/prepregnancy hypertension | |
| Treatment History | N/A | |
| Group | matched cases, severe CHD offspring(Treatment) | matched controls(Control) |
| Number | 60(total:186) | 40(total:186) |
| Age | mothers:adults; children(<2 years) | mothers:adults; children(<2 years) |
| Gender (Male: Female) | 0:60 | 0:40 |
| Marker Level | 0.323 | 0.215 |
